I love the sign idea that Angela left. One of my great struggles, as Angela noted, is when students raise their hand during instruction you run the gamut of possibilities. I know you were looking for a way to gesture what was needed, but it may be helpful to have students use a different "gesture" for personal needs. If it pertains to the lesson (a direct question, the need for a pencil because they won't be able to work on the concept without one, etc) then a hand raise is fine. If it DOES NOT pertain to the lesson (bathroom, tissue, nurse, etc) then they put their hand on their heart/chest to signal a personal need. At that time you could simply point, place your hand on you heart/chest, or something similar to let them know you've seen them and will get to them when time allows and is appropriate. Then you have to remember to get to them during the appropriate time. That's where I struggle - remembering.